The advances in image guided radiotherapy (IGRT) lead to an significant increase in
treatment quality of cancer patients. However the guidance of radiotherapy based on
X-Ray shows limitations and never translated into ...
Tools to manipulate genetic information without interfering at the DNA level are highly desirable in medicine and the life sciences. Recently, our group introduced the first engineered, RNA-guided deaminase. The approach ...
A major obstacle on the way to understand the molecular pathogenesis of Parkinson’s disease (PD) and to develop disease-modifying treatments is the lack of suitable model systems that capture the relevant molecular events ...
Die Arzneimittelentwicklung ist ein sehr zeit- und kostenaufwändiger Prozess, der viele in-vitro- und in-vivo-Studien erfordert. Trotz zahlreicher Studien scheitern über 90 % der Arzneimittel-kandidaten in der präklinischen ...