A major obstacle on the way to understand the molecular pathogenesis of Parkinson’s disease (PD) and to develop disease-modifying treatments is the lack of suitable model systems that capture the relevant molecular events ...
Die Arzneimittelentwicklung ist ein sehr zeit- und kostenaufwändiger Prozess, der viele in-vitro- und in-vivo-Studien erfordert. Trotz zahlreicher Studien scheitern über 90 % der Arzneimittel-kandidaten in der präklinischen ...
Staphylococcus aureus (S. aureus) is a gram-positive bacterium with a “split personality”. Staphylococci are part of the normal skin flora, but can also cause skin and wound infections as well as fatal septicaemia. The ...
At the beginning of this thesis, we illustrate the power-to-protein concept by conducting a comparative analysis between all the systems that have been implemented to perform carbon fixation into microbial protein using ...
Delayed fracture healing is a burden for patients as well as the health care system. Moreover, 5–10% of all fractures show a delay in healing or even result in non-unions. One of the major risk factors for developing a ...
Osteoporose ist zu einer Erkrankung des Knochenstoffwechsels geworden, von der zunehmend ältere Patienten betroffen sind und die zu einer enormen finanziellen Belastung und Beeinträchtigung der Lebensqualität führen. In ...