Auflistung nach Autor "Heim, Christopher"

Anzeige der Dokumente 1-12 von 12

Cereblon neo-substrate binding mimics the recognition of the cyclic imide degron

Heim, Christopher; Kirchgäßner, Sören; Schwarzer, Dirk; Hartmann, Marcus (2023)
Chemical Ligand Space of Cereblon

Boichenko, Iuliia; Deiss, Silvia; Heim, Christopher; Albrecht, Reinhard; Lupas, Andrei N.; Hernandez Alvarez, Birte; Bär, Kerstin; Hartmann, Marcus (2018)
De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives

Heim, Christopher; Hernandez Alvarez, Birte; Bär, Kerstin; Hartmann, Marcus (2019)
High-resolution structures of the bound effectors avadomide (CC-122) and iberdomide (CC-220) highlight advantages and limitations of the MsCI4 soaking system

Heim, Christopher; Hartmann, Marcus (2022)
Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon

Heim, Christopher; Schwarzer, Dirk; Kirchgäßner, Sören; Hartmann, Marcus (2022)
Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G

Heim, Christopher; Hartmann, Marcus (2016)
Natural and artificial ligands of cereblon and their therapeutic potential

Heim, Christopher (2024-12-31)

Dissertation ist gesperrt bis 31. Dezember 2024 !
On the correlation of cereblon binding, fluorination and antiangiogenic properties of immunomodulatory drugs

Heim, Christopher; Maiwald, Samuel; Hartmann, Marcus (2021)
Replacing the phthalimide core in thalidomide with benzotriazole

Heim, Christopher; Maiwald, Samuel; Hartmann, Marcus (2022)
Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay

Maiwald, Samuel; Heim, Christopher; Hernandez Alvarez, Birte; Hartmann, Marcus (2021)
Synthesis of novel glutarimide derivatives via the Ugi multicomponent reaction: affinity towards the E3 ubiquitin ligase substrate receptor Cereblon

Heim, Christopher; Hartmann, Marcus (2022)
Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines

Heim, Christopher; Hartmann, Marcus (2023)

Anzeige der Dokumente 1-12 von 12

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Auflistung nach Autor "Heim, Christopher"

Auflistung nach Autor "Heim, Christopher"

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