Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines

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Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines

Autor(en): Krasavin, Mikhail; Adamchik, Maria; Bubyrev, Andrey; Heim, Christopher; Maiwald, Samuel; Zhukovsky, Daniil; Zhmurov, Petr; Bunev, Alexander; Hartmann, Marcus D.
Tübinger Autor(en):
Heim, Christopher
Hartmann, Marcus
Erschienen in: European Journal of Medicinal Chemistry (2023), Bd. 246, Article 114990
Verlagsangabe: Elsevier France - Editions Scientifiques Medicales Elsevier
Sprache: Englisch
Referenz zum Volltext: http://dx.doi.org/10.1016/j.ejmech.2022.114990
ISSN: 0223-5234
DDC-Klassifikation: 540 - Chemie
Dokumentart: Wissenschaftlicher Artikel
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