Severe congenital neutropenia (CN) is a pre-leukemia bone marrow failure syndrome with profoundly diminished terminal granulocytic differentiation of hematopoietic stem cells (HSCs). Life-long treatment with granulocyte-colony ...

Cancer is a leading cause of death worldwide and global numbers of cases are growing rapidly. One third of all cancer deaths can be attributed to exposure to the five leading risk factors tobacco and alcohol consumption, ...