dc.contributor.advisor |
Wiesner, Silke (Dr.) |
|
dc.contributor.author |
Ruetalo Buschinger, Natalia |
|
dc.date.accessioned |
2018-01-09T10:38:30Z |
|
dc.date.available |
2018-01-09T10:38:30Z |
|
dc.date.issued |
2020-01-10 |
|
dc.identifier.other |
1688128433 |
de_DE |
dc.identifier.uri |
http://hdl.handle.net/10900/79633 |
|
dc.identifier.uri |
http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-796334 |
de_DE |
dc.identifier.uri |
http://dx.doi.org/10.15496/publikation-21031 |
|
dc.description.abstract |
Nedd4-family enzymes play key roles in the establishment and regulation of both developmental and carcinogenic processes. Hence, profound studies of the catalytic mechanisms and detailed analysis of protein-specific regulation of these enzymes as presented in this thesis, contribute significantly to the understanding of HECT ligases but also may have implications for the development of pharmaceutical inhibitors. |
en |
dc.language.iso |
en |
de_DE |
dc.publisher |
Universität Tübingen |
de_DE |
dc.rights |
ubt-podno |
de_DE |
dc.rights.uri |
http://tobias-lib.uni-tuebingen.de/doku/lic_ohne_pod.php?la=de |
de_DE |
dc.rights.uri |
http://tobias-lib.uni-tuebingen.de/doku/lic_ohne_pod.php?la=en |
en |
dc.subject.classification |
Proteine , Magnetische Kernresonanz , Ligasen , Biochemie , Ubiquitinierung , Ubiquitin |
de_DE |
dc.subject.ddc |
570 |
de_DE |
dc.subject.other |
Biochemistry |
en |
dc.subject.other |
Protein |
en |
dc.subject.other |
NMR |
en |
dc.subject.other |
Ubiquitination |
en |
dc.subject.other |
E3 ligases |
en |
dc.subject.other |
Nedd4-family |
en |
dc.title |
Mechanisms underlying the regulation of Nedd4-family E3 Ubiquitin ligases |
en |
dc.type |
PhDThesis |
de_DE |
dcterms.dateAccepted |
2017-12-08 |
|
utue.publikation.fachbereich |
Biochemie |
de_DE |
utue.publikation.fakultaet |
7 Mathematisch-Naturwissenschaftliche Fakultät |
de_DE |