The Role of Cyclic Guanosine Monophosphate Signaling in Biomechanics

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dc.contributor.advisor Schäffer, Tilman (Prof. Dr.)
dc.contributor.author Balmes, Aylin
dc.date.accessioned 2025-01-03T08:27:59Z
dc.date.available 2025-01-03T08:27:59Z
dc.date.issued 2026-12-12
dc.identifier.uri http://hdl.handle.net/10900/159802
dc.identifier.uri http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-1598027 de_DE
dc.identifier.uri http://dx.doi.org/10.15496/publikation-101134
dc.identifier.uri http://nbn-resolving.org/urn:nbn:de:bsz:21-dspace-1598026 de_DE
dc.identifier.uri http://nbn-resolving.org/urn:nbn:de:bsz:21-dspace-1598021 de_DE
dc.description.abstract Cyclic guanosine monophosphate (cGMP) is an important second messenger that is involved in the regulation of many physiological and pathological processes. The investigation of biomechanical properties (e.g. stiffness) can provide valuable insights on cell behavior. However, the influence of cGMP signaling on biomechanical properties of cells remains mostly unknown. In this thesis the role of cGMP signaling in biomechanics is investigated in platelets, vascular smooth muscle cells (VSMCs), and dorsal root ganglion (DRG) neurons. For this, different techniques were used, including atomic force microscopy (AFM), scanning ion conductance microscopy (SICM), and pulse wave velocity (PWV) measurements. en
dc.description.abstract Die Dissertation ist gesperrt bis zum 12. Dezember 2026 ! de_DE
dc.language.iso en de_DE
dc.publisher Universität Tübingen de_DE
dc.rights ubt-podno de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_ohne_pod.php?la=de de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_ohne_pod.php?la=en en
dc.subject.ddc 500 de_DE
dc.title The Role of Cyclic Guanosine Monophosphate Signaling in Biomechanics en
dc.type PhDThesis de_DE
dcterms.dateAccepted 2024-12-13
utue.publikation.fachbereich Physik de_DE
utue.publikation.fakultaet 7 Mathematisch-Naturwissenschaftliche Fakultät de_DE
utue.publikation.noppn yes de_DE

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