Auflistung nach Autor "Zanger, Ulrich M."

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A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort

Klein, Kathrin; Tremmel, Roman; Winter, Stefan; Schwab, Matthias; Zanger, Ulrich M.; Schäffeler, Elke (2019)
A Systematic Comparison of the Impact of Inflammatory Signaling on Absorption, Distribution, Metabolism, and Excretion Gene Expression and Activity in Primary Human Hepatocytes and HepaRG Cells

Klein, Marcus; Thomas, Maria; Hofmann, Ute; Zanger, Ulrich M. (2015)
Activating and Inhibitory Functions of WNT/beta-Catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells

Thomas, Maria; Bayha, Christine; Vetter, Silvia; Hofmann, Ute; Schwarz, Michael; Zanger, Ulrich M. (2015)
Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma

Tremmel, Roman; Zanger, Ulrich M. (2016)
beta-Defensin 1 ls Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor

Klag, Thomas; Thomas, Maria; Ehmann, Dirk; Courth, Lioba; Mailänder-Sánchez, Daniela Isabel; Stange, Eduard F.; Berg, Christoph Peter; Malek, Nisar Peter; Zanger, Ulrich M.; Wehkamp, Jan (2018)
Clinical relevance of DPYD variants c.1679T > G, c.1236G > A/HapB3, and c.1601G > A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

Schwab, Matthias; Zanger, Ulrich M. (2015)
Coordinating Role of RXR alpha in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling

Keller, Roland; Klein, Marcus; Thomas, Maria; Zell, Andreas; Zanger, Ulrich M.; Dräger, Andreas (2016)
Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression

Tremmel, Roman; Klein, Kathrin; Winter, Stefan; Schäffeler, Elke; Schwab, Matthias; Zanger, Ulrich M.; Battke, Florian (2020)
Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells

Heintze, Tamara Sonja; Klein, Kathrin; Hofmann, Ute; Zanger, Ulrich M. (2021)
Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates

Weiß, Frederik; Klein, Kathrin; Planatscher, Hannes; Zanger, Ulrich M.; Joos, Thomas; Hammer, Helen; Pötz, Oliver (2018)
Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism

Zanger, Ulrich M. (2012)
Effect of Genetic Variability in the CYP4F2, CYP4F11, and CYP4F12 Genes on Liver mRNA Levels and Warfarin Response

Klein, Kathrin; Zanger, Ulrich M. (2017)
Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis

Heintze, Tamara Sonja; Schmidlin, Thierry; Hofmann, Ute; Zanger, Ulrich M.; Schwab, Matthias; Klein, Kathrin (2021)
Expression Variability of Absorption, Distribution, Metabolism, Excretion-Related MicroRNAs in Human Liver: Influence of Nongenetic Factors and Association with Gene Expressions

Rieger, Jessica Karin; Klein, Kathrin; Winter, Stefan; Zanger, Ulrich M. (2013)
Factors Affecting Interindividual Variability of Hepatic UGT2B17 Protein Expression Examined Using a Novel Specific Monoclonal Antibody

Klein, Kathrin; Zanger, Ulrich M. (2019)
Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1

Tremmel, Roman; Klein, Kathrin; Winter, Stefan; Schäffeler, Elke; Zanger, Ulrich M. (2016)
Genetic Markers of Toxicity From Capecitabine and Other Fluorouracil-Based Regimens: Investigation in the QUASAR2 Study, Systematic Review, and Meta-Analysis

Zanger, Ulrich M.; Schwab, Matthias (2014)
Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites

Kerb, Reinhold; Turpeinen, Miia; Schroth, Werner; Ganchev, Boian; Igel, Svitlana; Zanger, Ulrich M.; Brauch, Hiltrud; Schwab, Matthias; Mürdter, Thomas E.; Böhmer, Gabriele M.; Schäffeler, Elke (2012)
Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

Nies, Anne; Burk, Oliver; Winter, Stefan; Zanger, Ulrich M.; Schwab, Matthias; Schäffeler, Elke (2013)
Genetics, Epigenetics, and Regulation of Drug-Metabolizing Cytochrome P450 Enzymes

Thomas, Maria; Tremmel, Roman; Kandel, Benjamin A.; Klein, Marcus; Magdy, Tarek; Zanger, Ulrich M.; Klein, Kathrin; Rieger, Jessica Karin (2014)

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