Clinical relevance of DPYD variants c.1679T > G, c.1236G > A/HapB3, and c.1601G > A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

Meulendijks, Didier; Henricks, Linda M.; Sonke, Gabe S.; Deenen, Maarten J.; Froehlich, Tanja K.; Amstutz, Ursula; Largiader, Carlo R.; Jennings, Barbara A.; Marinaki, Anthony M.; Sanderson, Jeremy D.; Kleibl, Zdenek; Kleiblova, Petra; Schwab, Matthias; Zanger, Ulrich M.; Palles, Claire; Tomlinson, Ian; Gross, Eva; van Kuilenburg, Andre B. P.; Punt, Cornelis J. A.; Koopman, Miriam; Beijnen, Jos H.; Cats, Annemieke; Schellens, Jan H. M.

Clinical relevance of DPYD variants c.1679T > G, c.1236G > A/HapB3, and c.1601G > A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

Author:

Meulendijks, Didier; Henricks, Linda M.; Sonke, Gabe S.; Deenen, Maarten J.; Froehlich, Tanja K.; Amstutz, Ursula; Largiader, Carlo R.; Jennings, Barbara A.; Marinaki, Anthony M.; Sanderson, Jeremy D.; Kleibl, Zdenek; Kleiblova, Petra; Schwab, Matthias; Zanger, Ulrich M.; Palles, Claire; Tomlinson, Ian; Gross, Eva; van Kuilenburg, Andre B. P.; Punt, Cornelis J. A.; Koopman, Miriam; Beijnen, Jos H.; Cats, Annemieke; Schellens, Jan H. M.

Tübinger Autor(en):

Schwab, Matthias
Zanger, Ulrich M.

Published in:

Lancet Oncology (2015), Bd. 16, H. 16, S. 1639-1650

Verlagsangabe:

Elsevier Science Inc

Language:

English

Full text:

http://dx.doi.org/10.1016/S1470-2045(15)00286-7

ISSN:

1474-5488