Auflistung nach Autor "Günther, Marcel Benjamin"

Anzeige der Dokumente 1-10 von 10

Design of a Two-in-One Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites

Wittlinger, Florian; Laufer, Stefan; Günther, Marcel Benjamin (2022)
Design, Synthese und Optimierung neuer mutationsspezifischer EGFR Inhibitoren

Günther, Marcel Benjamin (2017)
Fighting cancer drug resistance: Opportunities and challenges for mutation-specific EGFR inhibitors

Juchum, Michael; Laufer, Stefan; Günther, Marcel Benjamin (2015)
Lung Cancer: EGFR Inhibitors with Low Nanomolar Activity against a Therapy-Resistant L858R/T790M/C797S Mutant

Juchum, Michael; Laufer, Stefan; Günther, Marcel Benjamin (2016)
Structural Basis for EGFR Mutant Inhibition by Trisubstituted Imidazole Inhibitors

Wittlinger, Florian; Günther, Marcel Benjamin; Laufer, Stefan (2020)
Synthesis and structure-activity-relationship of 3,4-Diaryl-1H-pyrrolo[2,3-b]pyridines as irreversible Inhibitors of mutant EGFR-L858R/T790M

Günther, Marcel Benjamin; Laux, Julian; Laufer, Stefan (2019)
Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond

Lange, Andreas; Zimmermann, Markus O.; Heidrich, Johannes; Hennig, Susanne; Schall, Christoph; Sievers-Engler, Adrian; Ansideri, Francesco; Koch, Pierre; Stehle, Thilo; Laufer, Stefan; Günther, Marcel Benjamin; Büttner, Felix Michael; Lämmerhofer, Michael; Böckler, Frank (2015)
Tetra-Substituted Pyridinylimidazoles As Dual Inhibitors of p38 alpha Mitogen-Activated Protein Kinase and c-Jun N-Terminal Kinase 3 for Potential Treatment of Neurodegenerative Diseases

Muth, Felix; Fischer, Sabine; Maier, Julia; Rothbauer, Ulrich; Koch, Pierre; Günther, Marcel Benjamin; Bauer, Silke Mona; Laufer, Stefan; Döring, Eva (2015)
Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping

Juchum, Michael; Sievers-Engler, Adrian; Laufer, Stefan; Günther, Marcel Benjamin; Döring, Eva; Lämmerhofer, Michael (2017)
Trisubstituted Pyridinylimidazoles as Potent Inhibitors of the Clinically Resistant L858R/T790M/C797S EGFR Mutant: Targeting of Both Hydrophobic Regions and the Phosphate Binding Site

Juchum, Michael; Laufer, Stefan; Günther, Marcel Benjamin; Döring, Eva (2017)

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Auflistung nach Autor "Günther, Marcel Benjamin"

Auflistung nach Autor "Günther, Marcel Benjamin"

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