Trisubstituted Pyridinylimidazoles as Potent Inhibitors of the Clinically Resistant L858R/T790M/C797S EGFR Mutant: Targeting of Both Hydrophobic Regions and the Phosphate Binding Site

Author:

Gunther, Marcel; Lategahn, Jonas; Juchum, Michael; Doring, Eva; Keul, Marina; Engel, Julian; Tumbrink, Hannah L.; Rauh, Daniel; Laufer, Stefan

Tübinger Autor(en):

Published in:

Journal of Medicinal Chemistry (2017), Bd. 60, H. 13, S. 5613-5637

Verlagsangabe:

Amer Chemical Soc

Language:

English

Full text:

ISSN:

1520-4804

DDC Classifikation:

540 - Chemistry and allied sciences

Dokumentart:

Artikel

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