Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification

Vaidyanathan, Sriram; Azizian, Krist T.; Haque, A. K. M. Ashiqul; Henderson, Jordana M.; Hendel, Ayal; Shore, Sabrina; Antony, Justin S.; Hogrefe, Richard, I; Kormann, Michael S. D.; Porteus, Matthew H.; McCaffrey, Anton P.

dc.contributor.author	Haque, A. K. M. Ashiqul
dc.contributor.author	Selvaraj, Justin Antony
dc.contributor.author	Kormann, Michael
dc.date.accessioned	2019-08-13T13:43:24Z
dc.date.available	2019-08-13T13:43:24Z
dc.date.issued	2018
dc.identifier.issn	2162-2531
dc.identifier.uri	http://hdl.handle.net/10900/91449
dc.language.iso	en	de_DE
dc.publisher	Cell Press	de_DE
dc.relation.uri	http://dx.doi.org/10.1016/j.omtn.2018.06.010	de_DE
dc.subject.ddc	610	de_DE
dc.title	Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification	de_DE
dc.type	Article	de_DE
utue.quellen.id	20190321153956_01165
utue.publikation.seiten	530-542	de_DE
utue.personen.roh	Vaidyanathan, Sriram
utue.personen.roh	Azizian, Krist T.
utue.personen.roh	Haque, A. K. M. Ashiqul
utue.personen.roh	Henderson, Jordana M.
utue.personen.roh	Hendel, Ayal
utue.personen.roh	Shore, Sabrina
utue.personen.roh	Antony, Justin S.
utue.personen.roh	Hogrefe, Richard, I
utue.personen.roh	Kormann, Michael S. D.
utue.personen.roh	Porteus, Matthew H.
utue.personen.roh	McCaffrey, Anton P.
dcterms.isPartOf.ZSTitelID	Molecular Therapy - Nucleic Acids	de_DE
dcterms.isPartOf.ZS-Volume	12	de_DE
utue.fakultaet	04 Medizinische Fakultät	de_DE