Molecular mechanisms of messenger RNA decapping

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Dokumentart: Dissertation
Date: 2021-07-24
Language: English
Faculty: 7 Mathematisch-Naturwissenschaftliche Fakultät
Department: Biochemie
Advisor: Stehle, Thilo (Prof. Dr.)
Day of Oral Examination: 2019-07-24
DDC Classifikation: 570 - Life sciences; biology
Other Keywords:
mRNA decay, decapping
License: Publishing license including print on demand
Order a printed copy: Print-on-Demand
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The work presented in this doctoral thesis describes biochemical and structural investigations of the molecular mechanisms of messenger RNA decapping—a critical step in one of the major cytoplasmic messenger RNA decay pathways. Decapping, mediated by the DCP2 enzyme, is the removal of the protective methylguanosine cap

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