Molecular mechanisms of messenger RNA decapping

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Molecular mechanisms of messenger RNA decapping

Muthukumar, Sowndarya
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URI: http://hdl.handle.net/10900/91206
http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-912065
http://dx.doi.org/10.15496/publikation-32587
http://nbn-resolving.org/urn:nbn:de:bsz:21-dspace-912068
http://nbn-resolving.org/urn:nbn:de:bsz:21-dspace-912067
Dokumentart: PhDThesis
Date: 2021-07-24
Language: English
Faculty: 7 Mathematisch-Naturwissenschaftliche Fakultät
Department: Biochemie
Advisor: Stehle, Thilo (Prof. Dr.)
Day of Oral Examination: 2019-07-24
DDC Classifikation: 570 - Life sciences; biology
Other Keywords:
mRNA decay, decapping
License: http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=de http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=en
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Abstract:

The work presented in this doctoral thesis describes biochemical and structural investigations of the molecular mechanisms of messenger RNA decapping—a critical step in one of the major cytoplasmic messenger RNA decay pathways. Decapping, mediated by the DCP2 enzyme, is the removal of the protective methylguanosine cap

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