Molecular mechanisms of messenger RNA decapping

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URI: http://hdl.handle.net/10900/91206
http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-912065
http://dx.doi.org/10.15496/publikation-32587
Dokumentart: Dissertation
Date: 2021-07-24
Language: English
Faculty: 7 Mathematisch-Naturwissenschaftliche Fakultät
Department: Biochemie
Advisor: Stehle, Thilo (Prof. Dr.)
Day of Oral Examination: 2019-07-24
DDC Classifikation: 570 - Life sciences; biology
Other Keywords:
mRNA decay, decapping
License: Publishing license including print on demand
Order a printed copy: Print-on-Demand
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Inhaltszusammenfassung:

Dissertation ist gesperrt bis 24.07.2019

Abstract:

The work presented in this doctoral thesis describes biochemical and structural investigations of the molecular mechanisms of messenger RNA decapping—a critical step in one of the major cytoplasmic messenger RNA decay pathways. Decapping, mediated by the DCP2 enzyme, is the removal of the protective methylguanosine cap

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