An algorithm to build a multi-genome reference and its application

DSpace Repository


Dokumentart: PhDThesis
Date: 2018-12-17
Language: English
Faculty: 7 Mathematisch-Naturwissenschaftliche Fakultät
Department: Biologie
Advisor: Weigel, Detlef (Prof. Dr.)
Day of Oral Examination: 2018-10-04
DDC Classifikation: 004 - Data processing and computer science
Keywords: Bioinformatik
Other Keywords:
reference genome
graph theory
Order a printed copy: Print-on-Demand
Show full item record


In this dissertation a method is proposed that allows a comparison against several high-quality reference genomes simultaneously. To this end, an algorithm has been developed that creates a graph as a multi-genome reference to remove the reference bias and to simplify downstream analysis.

This item appears in the following Collection(s)