Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping

dc.contributor.author	Juchum, Michael
dc.contributor.author	Sievers-Engler, Adrian
dc.contributor.author	Laufer, Stefan
dc.contributor.author	Günther, Marcel Benjamin
dc.contributor.author	Döring, Eva
dc.contributor.author	Lämmerhofer, Michael
dc.date.accessioned	2017-09-27T11:33:09Z
dc.date.available	2017-09-27T11:33:09Z
dc.date.issued	2017
dc.identifier.issn	1520-4804
dc.identifier.uri	http://hdl.handle.net/10900/77972
dc.language.iso	en	de_DE
dc.publisher	Amer Chemical Soc	de_DE
dc.relation.uri	http://dx.doi.org/10.1021/acs.jmedchem.7b00178	de_DE
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject.ddc	540	de_DE
dc.title	Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping	de_DE
dc.type	Article	de_DE
utue.quellen.id	20170815222223_00475
utue.publikation.seiten	4636-4656	de_DE
utue.personen.roh	Juchum, Michael
utue.personen.roh	Guenther, Marcel
utue.personen.roh	Doering, Eva
utue.personen.roh	Sievers-Engler, Adrian
utue.personen.roh	Laemmerhofer, Michael
utue.personen.roh	Laufer, Stefan
dcterms.isPartOf.ZSTitelID	Journal of Medicinal Chemistry	de_DE
dcterms.isPartOf.ZS-Issue	11	de_DE
dcterms.isPartOf.ZS-Volume	60	de_DE
utue.fakultaet	07 Mathematisch-Naturwissenschaftliche Fakultät	de_DE