A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-beta and neuroinflammation in APP transgenic mice

Neumann, Ulf; Rueeger, Heinrich; Machauer, Rainer; Veenstra, Siem Jacob; Lueoend, Rainer M.; Tintelnot-Blomley, Marina; Laue, Grit; Beltz, Karen; Vogg, Barbara; Schmid, Peter; Frieauff, Wilfried; Shimshek, Derya R.; Staufenbiel, Matthias; Jacobson, Laura H.

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A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-beta and neuroinflammation in APP transgenic mice

Author:

Neumann, Ulf; Rueeger, Heinrich; Machauer, Rainer; Veenstra, Siem Jacob; Lueoend, Rainer M.; Tintelnot-Blomley, Marina; Laue, Grit; Beltz, Karen; Vogg, Barbara; Schmid, Peter; Frieauff, Wilfried; Shimshek, Derya R.; Staufenbiel, Matthias; Jacobson, Laura H.

Tübinger Autor(en):

Staufenbiel, Matthias

Published in:

Molecular Neurodegeneration (2015), Bd. 10, Article 44

Verlagsangabe:

Biomed Central Ltd

Language:

English

Full text:

http://dx.doi.org/10.1186/s13024-015-0033-8

ISSN:

1750-1326