Carboxymefloquine, the Major Metabolite of the Antimalarial Drug Mefloquine, Induces Drug-Metabolizing Enzyme and Transporter Expression by Activation of Pregnane X Receptor

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Carboxymefloquine, the Major Metabolite of the Antimalarial Drug Mefloquine, Induces Drug-Metabolizing Enzyme and Transporter Expression by Activation of Pregnane X Receptor

Author: Piedade, Rita; Traub, Stefanie; Bitter, Andreas; Nuessler, Andreas K.; Gil, Jose P.; Schwab, Matthias; Burk, Oliver
Tübinger Autor(en):
Schwab, Matthias
Nüssler, Andreas
Published in: Antimicrobial Agents and Chemotherapy (2015), Bd. 59, H. 1, S. 96-104
Verlagsangabe: Amer Soc Microbiology
Language: English
Full text: http://dx.doi.org/10.1128/ACC.04140.14
ISSN: 0066-4804
DDC Classifikation: 570 - Life sciences; biology
610 - Medicine and health
Dokumentart: Article
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