Isoniazid Mediates the CYP2B6*6 Genotype-Dependent Interaction between Efavirenz and Antituberculosis Drug Therapy through Mechanism-Based Inactivation of CYP2A6

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Isoniazid Mediates the CYP2B6*6 Genotype-Dependent Interaction between Efavirenz and Antituberculosis Drug Therapy through Mechanism-Based Inactivation of CYP2A6

Author: Court, Michael H.; Almutairi, Fawziah E.; Greenblatt, David J.; Hazarika, Suwagmani; Sheng, Hongyan; Klein, Kathrin; Zanger, Ulrich M.; Bourgea, Joanne; Patten, Christopher J.; Kwara, Awewura
Tübinger Autor(en):
Klein, Kathrin
Zanger, Ulrich M.
Published in: Antimicrobial Agents and Chemotherapy (2014), Bd. 58, H. 7, S. 4145-4152
Verlagsangabe: Amer Soc Microbiology
Language: English
Full text: http://dx.doi.org/10.1128/AAC.02532-14
ISSN: 0066-4804
DDC Classifikation: 570 - Life sciences; biology
610 - Medicine and health
Dokumentart: Article
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