RNA and Imidazoquinolines Are Sensed by Distinct TLR7/8 Ectodomain Sites Resulting in Functionally Disparate Signaling Events

Colak, Elif; Leslie, Alasdair; Zausmer, Kieran; Khatamzas, Elham; Kubarenko, Andriy V.; Pichulik, Tica; Klimosch, Sascha N.; Mayer, Alice; Siggs, Owen; Hector, Andreas; Fischer, Roman; Klesser, Benedikt; Rautanen, Anna; Frank, Martin; Hill, Adrian V. S.; Manoury, Benedicte; Beutler, Bruce; Hartl, Dominik; Simmons, Alison; Weber, Alexander N. R.

RNA and Imidazoquinolines Are Sensed by Distinct TLR7/8 Ectodomain Sites Resulting in Functionally Disparate Signaling Events

Author:

Colak, Elif; Leslie, Alasdair; Zausmer, Kieran; Khatamzas, Elham; Kubarenko, Andriy V.; Pichulik, Tica; Klimosch, Sascha N.; Mayer, Alice; Siggs, Owen; Hector, Andreas; Fischer, Roman; Klesser, Benedikt; Rautanen, Anna; Frank, Martin; Hill, Adrian V. S.; Manoury, Benedicte; Beutler, Bruce; Hartl, Dominik; Simmons, Alison; Weber, Alexander N. R.

Tübinger Autor(en):

Pichulik, Tica
Klimosch, Sascha Niclas
Hector, Andreas
Hartl, Dominik
Weber, Alexander N. R.

Published in:

Journal of Immunology (2014), Bd. 192, H. 12, S. 5963-5973

Verlagsangabe:

Amer Assoc Immunologists

Language:

English

Full text:

http://dx.doi.org/10.4049/jimmunol.1303058

ISSN:

0022-1767