Design, Synthesis and Characterization of Targeted and Calcium Responsive Nano-size Contrast Agents for Magnetic Resonance Neuroimaging

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Design, Synthesis and Characterization of Targeted and Calcium Responsive Nano-size Contrast Agents for Magnetic Resonance Neuroimaging

Gündüz, Serhat
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Description: PhDThesis
URI: http://hdl.handle.net/10900/55041
http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-550417
Dokumentart: PhDThesis
Date: 2014-07-31
Language: English
Faculty: 7 Mathematisch-Naturwissenschaftliche Fakultät
Department: Chemie
Advisor: Maier, Martin E. (Prof. Dr.)
Day of Oral Examination: 2014-07-17
DDC Classifikation: 540 - Chemistry and allied sciences
Keywords: Kontrastmittel
Other Keywords:
Neuroimaging
License: http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=de http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=en
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Abstract:

Magnetic resonance imaging (MRI) is a powerful imaging technique for biomedicine and neuroscience. The contrast agents (CAs) have been developed to help increasing signal intensity for high resolution MR images. Here we report the synthesis of novel multimodal and multivalent CA targeted to the protein (Neutr/strept) avidin and calcium responsive multivalent CAs for MR neuroimaging.

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