Neurotoxin detection in food using disposable AChE-biosensors

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dc.contributor Institut für Technische Biochemie, Allmandring 31, D - 70569 Stuttgart de_CH
dc.contributor Institut für Physikalische und Theoretische Chemie de_DE
dc.contributor.author Schulze, Holger de_DE
dc.contributor.author Villatte, Francois de_DE
dc.contributor.author Schmid, Rolf D. de_DE
dc.contributor.author Bachmann, Till T. de_DE
dc.contributor.other Gauglitz, Günter de_DE
dc.date.accessioned 2001-11-08 de_DE
dc.date.accessioned 2014-03-18T10:09:19Z
dc.date.available 2001-11-08 de_DE
dc.date.available 2014-03-18T10:09:19Z
dc.date.issued 2001 de_DE
dc.identifier.other 099400863 de_DE
dc.identifier.uri http://nbn-resolving.de/urn:nbn:de:bsz:21-opus-3318 de_DE
dc.identifier.uri http://hdl.handle.net/10900/48222
dc.description.abstract The extensive use of pesticides to protect agricultural crops necessitates reliable tools for the detection of residues in food and water, thus ensuring environmental protection and consumer safety. Neuroinhibitors such as organophosphates and carbamates are widely used in agriculture because of their high insecticidal activity and their rapid mineralisation in the environment. Since they do not only inhibit insect acetylcholinesterase (AChE) but also interfere with neural transmission in other organism, including humans, they represent a potential hazard for human health and environmental food chains, and thus require continuous assessment. Recent reports on organophosphate contamination in baby food have initiated the reassessment of permitted residual concentrations of these compounds in view of the US Food Quality Protection Act. Here we present a rapid detection method for neurotoxins in food, which can increase the number of tested foodstuff and thus improve the consumer safety. We developed a highly sensitive and rapid food analysis biosensor based on disposable screen-printed thickfilm electrodes. Matrix problems were solved by using isooctane as extraction solvent. The performance of this amperometric test was checked by three different food matrixes, namely orange juice, apple and peach baby food. The detection limit was comparable to chemical standard methods and met the requirements for monitoring the maximum residue levels in baby food set by the EU. en
dc.language.iso en de_DE
dc.publisher Universität Tübingen de_DE
dc.rights ubt-nopod de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_ubt-nopod.php?la=de de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_ubt-nopod.php?la=en en
dc.subject.classification Biosensor , Nervengift de_DE
dc.subject.ddc 540 de_DE
dc.subject.other Neurotoxin en
dc.title Neurotoxin detection in food using disposable AChE-biosensors en
dc.type Sonstiges de_DE
dc.date.updated 2005-01-13 de_DE
utue.publikation.fachbereich Sonstige - Chemie und Pharmazie de_DE
utue.publikation.fakultaet 7 Mathematisch-Naturwissenschaftliche Fakultät de_DE
dcterms.DCMIType Text de_DE
utue.publikation.typ report de_DE
utue.opus.id 331 de_DE
utue.publikation.source http://barolo.ipc.uni-tuebingen.de/biosensor2001/ de_DE

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