Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

Sturm, Dominik; Witt, Hendrik; Hovestadt, Volker; Dong-Anh Khuong-Quang; Jones, David T. W.; Konermann, Carolin; Pfaff, Elke; Toenjes, Marge; Sill, Martin; Bender, Sebastian; Kool, Marcel; Zapatka, Marc; Becker, Natalia; Zucknick, Manuela; Hielscher, Thomas; Liu, Xiao-Yang; Fontebasso, Adam M.; Ryzhova, Marina; Albrecht, Steffen; Jacob, Karine; Wolter, Marietta; Ebinger, Martin; Schuhmann, Martin U.; van Meter, Timothy; Fruehwald, Michael C.; Hauch, Holger; Pekrun, Arnulf; Radlwimmer, Bernhard; Niehues, Tim; von Komorowski, Gregor; Duerken, Matthias; Kulozik, Andreas E.; Madden, Jenny; Donson, Andrew; Foreman, Nicholas K.; Drissi, Rachid; Fouladi, Maryam; Scheurlen, Wolfram; von Deimling, Andreas; Monoranu, Camelia; Roggendorf, Wolfgang; Herold-Mende, Christel; Unterberg, Andreas; Kramm, Christof M.; Felsberg, Joerg; Hartmann, Christian; Wiestler, Benedikt; Wick, Wolfgang; Milde, Till; Witt, Olaf; Lindroth, Anders M.; Schwartzentruber, Jeremy; Faury, Damien; Fleming, Adam; Zakrzewska, Magdalena; Liberski, Pawel P.; Zakrzewski, Krzysztof; Hauser, Peter; Garami, Miklos; Klekner, Almos; Bognar, Laszlo; Morrissy, Sorana; Cavalli, Florence; Taylor, Michael D.; van Sluis, Peter; Koster, Jan; Versteeg, Rogier; Volckmann, Richard; Mikkelsen, Tom; Aldape, Kenneth; Reifenberger, Guido; Collins, V. Peter; Majewski, Jacek; Korshunov, Andrey; Lichter, Peter; Plass, Christoph; Jabado, Nada; Pfister, Stefan M.

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

Author:

Sturm, Dominik; Witt, Hendrik; Hovestadt, Volker; Dong-Anh Khuong-Quang; Jones, David T. W.; Konermann, Carolin; Pfaff, Elke; Toenjes, Marge; Sill, Martin; Bender, Sebastian; Kool, Marcel; Zapatka, Marc; Becker, Natalia; Zucknick, Manuela; Hielscher, Thomas; Liu, Xiao-Yang; Fontebasso, Adam M.; Ryzhova, Marina; Albrecht, Steffen; Jacob, Karine; Wolter, Marietta; Ebinger, Martin; Schuhmann, Martin U.; van Meter, Timothy; Fruehwald, Michael C.; Hauch, Holger; Pekrun, Arnulf; Radlwimmer, Bernhard; Niehues, Tim; von Komorowski, Gregor; Duerken, Matthias; Kulozik, Andreas E.; Madden, Jenny; Donson, Andrew; Foreman, Nicholas K.; Drissi, Rachid; Fouladi, Maryam; Scheurlen, Wolfram; von Deimling, Andreas; Monoranu, Camelia; Roggendorf, Wolfgang; Herold-Mende, Christel; Unterberg, Andreas; Kramm, Christof M.; Felsberg, Joerg; Hartmann, Christian; Wiestler, Benedikt; Wick, Wolfgang; Milde, Till; Witt, Olaf; Lindroth, Anders M.; Schwartzentruber, Jeremy; Faury, Damien; Fleming, Adam; Zakrzewska, Magdalena; Liberski, Pawel P.; Zakrzewski, Krzysztof; Hauser, Peter; Garami, Miklos; Klekner, Almos; Bognar, Laszlo; Morrissy, Sorana; Cavalli, Florence; Taylor, Michael D.; van Sluis, Peter; Koster, Jan; Versteeg, Rogier; Volckmann, Richard; Mikkelsen, Tom; Aldape, Kenneth; Reifenberger, Guido; Collins, V. Peter; Majewski, Jacek; Korshunov, Andrey; Lichter, Peter; Plass, Christoph; Jabado, Nada; Pfister, Stefan M.

Tübinger Autor(en):

Ebinger, Martin
Schuhmann, Martin Ulrich

Published in:

Cancer Cell (2012), Bd. 22, H. 4, S. 425-437

Verlagsangabe:

Cell Press

Language:

English

Full text:

http://dx.doi.org/10.1016/j.ccr.2012.08.024

ISSN:

1535-6108