Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

Bender, Sebastian; Tang, Yujie; Lindroth, Anders M.; Hovestadt, Volker; Jones, David T. W.; Kool, Marcel; Zapatka, Marc; Northcott, Paul A.; Sturm, Dominik; Wang, Wei; Radlwimmer, Bernhard; Hojfeldt, Jonas W.; Truffaux, Nathalene; Castel, David; Schubert, Simone; Ryzhova, Marina; Seker-Cin, Huriye; Gronych, Jan; Johann, Pascal David; Stark, Sebastian; Meyer, Jochen; Milde, Till; Schuhmann, Martin; Ebinger, Martin; Monoranu, Camelia-Maria; Ponnuswami, Anitha; Chen, Spenser; Jones, Chris; Witt, Olaf; Collins, V. Peter; von Deimling, Andreas; Jabado, Nada; Puget, Stephanie; Grill, Jacques; Helin, Kristian; Korshunov, Andrey; Lichter, Peter; Monje, Michelle; Plass, Christoph; Cho, Yoon-Jae; Pfister, Stefan M.

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

Author:

Bender, Sebastian; Tang, Yujie; Lindroth, Anders M.; Hovestadt, Volker; Jones, David T. W.; Kool, Marcel; Zapatka, Marc; Northcott, Paul A.; Sturm, Dominik; Wang, Wei; Radlwimmer, Bernhard; Hojfeldt, Jonas W.; Truffaux, Nathalene; Castel, David; Schubert, Simone; Ryzhova, Marina; Seker-Cin, Huriye; Gronych, Jan; Johann, Pascal David; Stark, Sebastian; Meyer, Jochen; Milde, Till; Schuhmann, Martin; Ebinger, Martin; Monoranu, Camelia-Maria; Ponnuswami, Anitha; Chen, Spenser; Jones, Chris; Witt, Olaf; Collins, V. Peter; von Deimling, Andreas; Jabado, Nada; Puget, Stephanie; Grill, Jacques; Helin, Kristian; Korshunov, Andrey; Lichter, Peter; Monje, Michelle; Plass, Christoph; Cho, Yoon-Jae; Pfister, Stefan M.

Tübinger Autor(en):

Schuhmann, Martin Ulrich
Ebinger, Martin

Published in:

Cancer Cell (2013), Bd. 24, H. 5, S. 660-672

Verlagsangabe:

Cell Press

Language:

English

Full text:

http://dx.doi.org/10.1016/j.ccr.2013.10.006

ISSN:

1535-6108