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Browsing 7 Mathematisch-Naturwissenschaftliche Fakultät by Author

Browsing 7 Mathematisch-Naturwissenschaftliche Fakultät by Author "Zanger, Ulrich M."

Now showing items 1-14 of 14

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort

Klein, Kathrin; Tremmel, Roman; Winter, Stefan; Fehr, Sarah; Battke, Florian; Scheurenbrand, Tim; Schaeffeler, Elke; Biskup, Saskia; Schwab, Matthias; Zanger, Ulrich M. (2019)
Coordinating Role of RXR alpha in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling

Keller, Roland; Klein, Marcus; Thomas, Maria; Draeger, Andreas; Metzger, Ute; Templin, Markus F.; Joos, Thomas O.; Thasler, Wolfgang E.; Zell, Andreas; Zanger, Ulrich M. (2016)
Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression

Tremmel, Roman; Klein, Kathrin; Battke, Florian; Fehr, Sarah; Winter, Stefan; Scheurenbrand, Tim; Schaeffeler, Elke; Biskup, Saskia; Schwab, Matthias; Zanger, Ulrich M. (2020)
Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates

Weiss, Frederik; Hammer, Helen S.; Klein, Kathrin; Planatscher, Hannes; Zanger, Ulrich M.; Noren, Agneta; Wegler, Christine; Artursson, Per; Joos, Thomas O.; Poetz, Oliver (2018)
Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis

Heintze, Tamara; Wilhelm, Denise; Schmidlin, Thierry; Hofmann, Ute; Zanger, Ulrich M.; Schwab, Matthias; Klein, Kathrin (2021)
Genetics, Epigenetics, and Regulation of Drug-Metabolizing Cytochrome P450 Enzymes

Zanger, U. M.; Klein, K.; Thomas, M.; Rieger, J. K.; Tremmel, R.; Kandel, B. A.; Klein, M.; Magdy, T. (2014)
Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver

Schroeder, A.; Klein, K.; Winter, S.; Schwab, M.; Bonin, M.; Zell, A.; Zanger, U. M. (2013)
No Activation of Human Pregnane X Receptor by Hyperforin-Related Phloroglucinols

Kandel, Benjamin A.; Ekins, Sean; Leuner, Kristina; Thasler, Wolfgang E.; Harteneck, Christian; Zanger, Ulrich M. (2014)
Novel CYP2B6 Enzyme Variants in a Rwandese Population: Functional Characterization and Assessment of In Silico Prediction Tools

Radloff, Robert; Gras, Alain; Zanger, Ulrich M.; Masquelier, Cecile; Arumugam, Karthik; Karasi, Jean-Claude; Arendt, Vic; Seguin-Devaux, Carole; Klein, Kathrin (2013)
Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia

Fujiwara, Ryoichi; Haag, Mathias; Schaeffeler, Elke; Nies, Anne T.; Zanger, Ulrich M.; Schwab, Matthias (2018)
The CYP2B6*6 Allele Significantly Alters the N-Demethylation of Ketamine Enantiomers In Vitro

Li, Yibai; Coller, Janet K.; Hutchinson, Mark R.; Klein, Kathrin; Zanger, Ulrich M.; Stanley, Nathan J.; Abell, Andrew D.; Somogyi, Andrew A. (2013)
The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes

Johaenning, Janina; Kroener, Patrick; Thomas, Maria; Zanger, Ulrich M.; Noerenberg, Astrid; Eichelbaum, Michel; Schwab, Matthias; Brauch, Hiltrud; Schroth, Werner; Muerdter, Thomas E. (2018)
Tri-Allelic Haplotypes Determine and Differentiate Functionally Normal Allele CYP2D6*2 and Impaired Allele CYP2D6*41

Zanger, Ulrich M.; Momoi, Kyoko; Hofmann, Ute; Schwab, Matthias; Klein, Kathrin (2021)
Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors

Riedmaier, A. Emami; Burk, O.; van Eijck, B. A. C.; Schaeffeler, E.; Klein, K.; Fehr, S.; Biskup, S.; Mueller, S.; Winter, S.; Zanger, U. M.; Schwab, M.; Nies, A. T. (2016)

Now showing items 1-14 of 14

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