A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders

Ryeznik, Yevgen; Hilgers, Ralf-Dieter; Heussen, Nicole; Comets, Emmanuelle; Mentre, France; Hendrickx, Niels; Karlsson, Mats O.; Hooker, Andrew C.; Hamdan, Alzahra; Chen, Xiaomei; Schuele, Rebecca; Synofzik, Matthis; Sverdlov, Oleksandr

dc.contributor.author	Synofzik, Matthis
dc.contributor.author	Schüle, Rebecca
dc.date.accessioned	2026-10-19T07:50:05Z
dc.date.available	2026-10-19T07:50:05Z
dc.date.issued	2025
dc.identifier.issn	2163-8306
dc.identifier.uri	http://hdl.handle.net/10900/184504
dc.language.iso	en	de_DE
dc.publisher	Hoboken : Wiley	de_DE
dc.relation.uri	http://dx.doi.org/10.1002/psp4.70082	de_DE
dc.subject.ddc	610	de_DE
dc.title	A Pharmacometrics-Informed Trial Simulation Framework for Optimizing Study Designs for Disease-Modifying Treatments in Rare Neurological Disorders	de_DE
dc.type	Article	de_DE
utue.quellen.id	20251118000000_01170
utue.publikation.seiten	1705-1714	de_DE
utue.personen.roh	Ryeznik, Yevgen
utue.personen.roh	Hilgers, Ralf-Dieter
utue.personen.roh	Heussen, Nicole
utue.personen.roh	Comets, Emmanuelle
utue.personen.roh	Mentre, France
utue.personen.roh	Hendrickx, Niels
utue.personen.roh	Karlsson, Mats O.
utue.personen.roh	Hooker, Andrew C.
utue.personen.roh	Hamdan, Alzahra
utue.personen.roh	Chen, Xiaomei
utue.personen.roh	Schuele, Rebecca
utue.personen.roh	Synofzik, Matthis
utue.personen.roh	Sverdlov, Oleksandr
dcterms.isPartOf.ZSTitelID	Cpt - Pharmacometrics & Systems Pharmacology	de_DE
dcterms.isPartOf.ZS-Issue	10	de_DE
dcterms.isPartOf.ZS-Volume	14	de_DE
utue.fakultaet	04 Medizinische Fakultät	de_DE