A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner

Sylvain, Aude; Stoehr, Natacha; Ma, Fupeng; Cernijenko, Artiom; Schroder, Martin; Khoshouei, Maryam; Vogelsanger, Melanie; Schoenboerner, Michel; Burke, Ashley; Rao, Pasupuleti; Solomon, Jonathan M.; Paulk, Joshiawa; Xu, Lei; Dawson, Janet; Begue, Damien; Lefeuvre, Peggy; Ahrne, Erik; Hofmann, Andreas; Dickson, Callum J.; Arabin, Philip; Zimmerlin, Alfred; Kiffe, Michael; Froehlicher, Mirjam; Boersig, Theresa; Elhajouji, Azeddine; Brichet, Murielle; Menon, Suchithra; Liu, Shanming; Mueller, Matthias; Wartchow, Charles A.; Lin, James; Gloria, Yamel Cardona; Dickhofer, Sabine; Weber, Alexander N. R.; Welzel, Tatjana; Kuemmerle-Deschner, Jasmin; Farady, Christopher J.; Pulz, Robert; Bornancin, Frederic; Buckley, Dennis L.; Bassi, Zuni I.

dc.contributor.author	Gloria, Yamel Cardona
dc.contributor.author	Weber, Alexander N. R.
dc.contributor.author	Welzel, Tatjana
dc.contributor.author	Dickhöfer, Sabine
dc.contributor.author	Kümmerle-Deschner, Jasmin
dc.date.accessioned	2026-08-24T08:45:23Z
dc.date.available	2026-08-24T08:45:23Z
dc.date.issued	2025
dc.identifier.issn	2451-9456
dc.identifier.uri	http://hdl.handle.net/10900/182485
dc.language.iso	en	de_DE
dc.publisher	Cambridge : Cell Press	de_DE
dc.relation.uri	http://dx.doi.org/10.1016/j.chembiol.2025.06.005	de_DE
dc.subject.ddc	570	de_DE
dc.title	A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner	de_DE
dc.type	Article	de_DE
utue.quellen.id	20251118000000_01480
utue.publikation.seiten	955-968	de_DE
utue.personen.roh	Sylvain, Aude
utue.personen.roh	Stoehr, Natacha
utue.personen.roh	Ma, Fupeng
utue.personen.roh	Cernijenko, Artiom
utue.personen.roh	Schroder, Martin
utue.personen.roh	Khoshouei, Maryam
utue.personen.roh	Vogelsanger, Melanie
utue.personen.roh	Schoenboerner, Michel
utue.personen.roh	Burke, Ashley
utue.personen.roh	Rao, Pasupuleti
utue.personen.roh	Solomon, Jonathan M.
utue.personen.roh	Paulk, Joshiawa
utue.personen.roh	Xu, Lei
utue.personen.roh	Dawson, Janet
utue.personen.roh	Begue, Damien
utue.personen.roh	Lefeuvre, Peggy
utue.personen.roh	Ahrne, Erik
utue.personen.roh	Hofmann, Andreas
utue.personen.roh	Dickson, Callum J.
utue.personen.roh	Arabin, Philip
utue.personen.roh	Zimmerlin, Alfred
utue.personen.roh	Kiffe, Michael
utue.personen.roh	Froehlicher, Mirjam
utue.personen.roh	Boersig, Theresa
utue.personen.roh	Elhajouji, Azeddine
utue.personen.roh	Brichet, Murielle
utue.personen.roh	Menon, Suchithra
utue.personen.roh	Liu, Shanming
utue.personen.roh	Mueller, Matthias
utue.personen.roh	Wartchow, Charles A.
utue.personen.roh	Lin, James
utue.personen.roh	Gloria, Yamel Cardona
utue.personen.roh	Dickhofer, Sabine
utue.personen.roh	Weber, Alexander N. R.
utue.personen.roh	Welzel, Tatjana
utue.personen.roh	Kuemmerle-Deschner, Jasmin
utue.personen.roh	Farady, Christopher J.
utue.personen.roh	Pulz, Robert
utue.personen.roh	Bornancin, Frederic
utue.personen.roh	Buckley, Dennis L.
utue.personen.roh	Bassi, Zuni I.
dcterms.isPartOf.ZSTitelID	Cell Chemical Biology	de_DE
dcterms.isPartOf.ZS-Issue	7	de_DE
dcterms.isPartOf.ZS-Volume	32	de_DE
utue.fakultaet	04 Medizinische Fakultät	de_DE