Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice

Rezaei, Ali; Kocsis-Jutka, Virag; Gunes, Zeynep I.; Zeng, Qing; Kislinger, Georg; Bauernschmitt, Franz; Isilgan, Huseyin Berkcan; Parisi, Laura R.; Kaya, Tugberk; Franzenburg, Soeren; Koppenbrink, Jonas; Knogler, Julia; Arzberger, Thomas; Farny, Daniel; Nuscher, Brigitte; Katona, Eszter; Dhingra, Ashutosh; Yang, Chao; Gouna, Garyfallia; Laclair, Katherine D.; Janjic, Aleksandar; Enard, Wolfgang; Zhou, Qihui; Hagan, Nellwyn; Ofengeim, Dimitry; Beltran, Eduardo; Gokce, Ozgun; Simons, Mikael; Liebscher, Sabine; Edbauer, Dieter

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Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice

Author:

Rezaei, Ali; Kocsis-Jutka, Virag; Gunes, Zeynep I.; Zeng, Qing; Kislinger, Georg; Bauernschmitt, Franz; Isilgan, Huseyin Berkcan; Parisi, Laura R.; Kaya, Tugberk; Franzenburg, Soeren; Koppenbrink, Jonas; Knogler, Julia; Arzberger, Thomas; Farny, Daniel; Nuscher, Brigitte; Katona, Eszter; Dhingra, Ashutosh; Yang, Chao; Gouna, Garyfallia; Laclair, Katherine D.; Janjic, Aleksandar; Enard, Wolfgang; Zhou, Qihui; Hagan, Nellwyn; Ofengeim, Dimitry; Beltran, Eduardo; Gokce, Ozgun; Simons, Mikael; Liebscher, Sabine; Edbauer, Dieter

Tübinger Autor(en):

Dhingra, Ashutosh

Published in:

Nature Communications (2025), Bd. 16 (1), Article 3442

Verlagsangabe:

Berlin : Nature Portfolio

Language:

English

Full text:

http://dx.doi.org/10.1038/s41467-025-58634-4

ISSN:

2041-1723