Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma

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Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma

Author: Tsiami, Foteini; Lago, Chiara; Pozza, Noemi; Piccioni, Federica; Zhao, Xuesong; Luelsberg, Fabienne; Root, David E.; Tiberi, Luca; Kool, Marcel; Schittenhelm, Jens; Bandopadhayay, Pratiti; Segal, Rosalind A.; Tabatabai, Ghazaleh; Merk, Daniel J.
Tübinger Autor(en):
Tsiami, Foteini
Schittenhelm, Jens
Tabatabai, Ghazaleh
Merk, Daniel J.
Published in: Acta Neuropathologica Communications (2024), Bd. 12, H. 1
Verlagsangabe: London : Bmc
Language: English
Full text: http://dx.doi.org/10.1186/s40478-024-01831-x
ISSN: 2051-5960
DDC Classifikation: 610 - Medicine and health
570 - Life sciences; biology
Dokumentart: Article
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