Targeting neuronal lysosomal dysfunction caused by beta-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct

Gehrlein, Alexandra; Udayar, Vinod; Anastasi, Nadia; Morella, Martino L. L.; Ruf, Iris; Brugger, Doris; von der Mark, Sophia; Thoma, Ralf; Rufer, Arne; Heer, Dominik; Pfahler, Nina; Jochner, Anton; Niewoehner, Jens; Wolf, Luise; Fueth, Matthias; Ebeling, Martin; Villasenor, Roberto; Zhu, Yanping; Deen, Matthew C. C.; Shan, Xiaoyang; Ehsaei, Zahra; Taylor, Verdon; Sidransky, Ellen; Vocadlo, David J. J.; Freskgard, Per-Ola; Jagasia, Ravi

Targeting neuronal lysosomal dysfunction caused by beta-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct

Autor(en):

Gehrlein, Alexandra; Udayar, Vinod; Anastasi, Nadia; Morella, Martino L. L.; Ruf, Iris; Brugger, Doris; von der Mark, Sophia; Thoma, Ralf; Rufer, Arne; Heer, Dominik; Pfahler, Nina; Jochner, Anton; Niewoehner, Jens; Wolf, Luise; Fueth, Matthias; Ebeling, Martin; Villasenor, Roberto; Zhu, Yanping; Deen, Matthew C. C.; Shan, Xiaoyang; Ehsaei, Zahra; Taylor, Verdon; Sidransky, Ellen; Vocadlo, David J. J.; Freskgard, Per-Ola; Jagasia, Ravi

Tübinger Autor(en):

Pfahler, Nina Marion

Erschienen in:

Nature Communications (2023), Bd. 14 (1), Article 2057

Verlagsangabe:

Berlin : Nature Portfolio

Sprache:

Englisch

Referenz zum Volltext:

http://dx.doi.org/10.1038/s41467-023-37632-4

ISSN:

2041-1723