Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion

Rejeski, Kai; Perez, Ariel; Iacoboni, Gloria; Blumenberg, Viktoria; Buecklein, Veit L.; Voelkl, Simon; Penack, Olaf; Albanyan, Omar; Stock, Sophia; Mueller, Fabian; Karschnia, Philipp; Petrera, Agnese; Reid, Kayla; Faramand, Rawan; Davila, Marco L.; Modi, Karnav; Dean, Erin A.; Bachmeier, Christina; von Bergwelt-Baildon, Michael; Locke, Frederick L.; Bethge, Wolfgang; Bullinger, Lars; Mackensen, Andreas; Barba, Pere; Jain, Michael D.; Subklewe, Marion

Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion

Author:

Rejeski, Kai; Perez, Ariel; Iacoboni, Gloria; Blumenberg, Viktoria; Buecklein, Veit L.; Voelkl, Simon; Penack, Olaf; Albanyan, Omar; Stock, Sophia; Mueller, Fabian; Karschnia, Philipp; Petrera, Agnese; Reid, Kayla; Faramand, Rawan; Davila, Marco L.; Modi, Karnav; Dean, Erin A.; Bachmeier, Christina; von Bergwelt-Baildon, Michael; Locke, Frederick L.; Bethge, Wolfgang; Bullinger, Lars; Mackensen, Andreas; Barba, Pere; Jain, Michael D.; Subklewe, Marion

Tübinger Autor(en):

Bethge, Wolfgang Andreas

Published in:

Science Advances (2023), Bd. 9 (38), Article eadg391

Verlagsangabe:

Washington : Amer Assoc Advancement Science

Language:

English

Full text:

http://dx.doi.org/10.1126/sciadv.adg3919

ISSN:

2375-2548