Enhancing the potential of optical coherence tomography in human myopia research

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Enhancing the potential of optical coherence tomography in human myopia research

Breher, Katharina
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URI: http://hdl.handle.net/10900/121776
http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-1217765
http://dx.doi.org/10.15496/publikation-63142
http://nbn-resolving.org/urn:nbn:de:bsz:21-dspace-1217765
http://nbn-resolving.org/urn:nbn:de:bsz:21-dspace-1217767
Dokumentart: PhDThesis
Date: 2021-12-15
Language: English
Faculty: 7 Mathematisch-Naturwissenschaftliche Fakultät
Department: Biologie
Advisor: Wahl, Siegfried (Prof. Dr.)
Day of Oral Examination: 2021-11-15
DDC Classifikation: 500 - Natural sciences and mathematics
570 - Life sciences; biology
610 - Medicine and health
Keywords: Kurzsichtigkeit , Auge , Optische Kohärenztomografie , Optik , Brechung , Aderhaut , Netzhaut
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Abstract:

The primary purpose of the work was to assess and enhance OCT-based retinal biomarkers used in human myopia research in the context of advancing OCT technologies. The individual studies provided insights into the repeatability of automated choroidal thickness measurements with spectral-domain and swept-source OCT. Moreover, the work assessed wide- eld topographical choroidal vascularity, retinal and foveal shape in relation to myopia. Finally, novel procedures of retinal shape measurements were compared to peripheral refraction as previously used method for this purpose.

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