A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria

Adoke, Yeka; Zoleko-Manego, Rella; Ouoba, Serge; Tiono, Alfred B.; Kaguthi, Grace; Bonzela, Juvencio Eduardo; Tran Thanh Duong; Nahum, Alain; Bouyou-Akotet, Marielle; Ogutu, Bernhards; Ouedraogo, Alphonse; Macintyre, Fiona; Jessel, Andreas; Laurijssens, Bart; Cherkaoui-Rbati, Mohammed H.; Cantalloube, Cathy; Marrast, Anne Claire; Bejuit, Raphael; White, David; Wells, Timothy N. C.; Wartha, Florian; Leroy, Didier; Kibuuka, Afizi; Mombo-Ngoma, Ghyslain; Ouattara, Daouda; Mugenya, Irene; Bui Quang Phuc; Bohissou, Francis; Mawili-Mboumba, Denise P.; Olewe, Fredrick; Soulama, Issiaka; Tinto, Halidou

A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria

Author:

Adoke, Yeka; Zoleko-Manego, Rella; Ouoba, Serge; Tiono, Alfred B.; Kaguthi, Grace; Bonzela, Juvencio Eduardo; Tran Thanh Duong; Nahum, Alain; Bouyou-Akotet, Marielle; Ogutu, Bernhards; Ouedraogo, Alphonse; Macintyre, Fiona; Jessel, Andreas; Laurijssens, Bart; Cherkaoui-Rbati, Mohammed H.; Cantalloube, Cathy; Marrast, Anne Claire; Bejuit, Raphael; White, David; Wells, Timothy N. C.; Wartha, Florian; Leroy, Didier; Kibuuka, Afizi; Mombo-Ngoma, Ghyslain; Ouattara, Daouda; Mugenya, Irene; Bui Quang Phuc; Bohissou, Francis; Mawili-Mboumba, Denise P.; Olewe, Fredrick; Soulama, Issiaka; Tinto, Halidou

Tübinger Autor(en):

Mombo-Ngoma, Ghyslain

Published in:

Malaria Journal (2021), Bd. 20, Article 222

Verlagsangabe:

Bmc

Language:

English

Full text:

http://dx.doi.org/10.1186/s12936-021-03749-4

ISSN:

1475-2875