Browsing Universitätsbibliographie by Author "Klein, Kathrin"

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Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential

Margaillan, Guillaume; Rouleau, Michele; Klein, Kathrin; Fallon, John K.; Caron, Patrick; Villeneuve, Lyne; Smith, Philip C.; Zanger, Ulrich M.; Guillemette, Chantal (2015)
Novel CYP2B6 Enzyme Variants in a Rwandese Population: Functional Characterization and Assessment of In Silico Prediction Tools

Radloff, Robert; Gras, Alain; Zanger, Ulrich M.; Masquelier, Cecile; Arumugam, Karthik; Karasi, Jean-Claude; Arendt, Vic; Seguin-Devaux, Carole; Klein, Kathrin (2013)
Peroxisome proliferator-activated receptor alpha, PPAR alpha, directly regulates transcription of cytochrome P450 CYP2C8

Thomas, Maria; Winter, Stefan; Klumpp, Britta; Turpeinen, Miia; Klein, Kathrin; Schwab, Matthias; Zanger, Ulrich M. (2015)
PharmVar GeneFocus: CYP2B6

Desta, Zeruesenay; El-Boraie, Ahmed; Gong, Li; Somogyi, Andrew A.; Lauschke, Volker M.; Dandara, Collet; Klein, Kathrin; Miller, Neil A.; Klein, Teri E.; Tyndale, Rachel F.; Whirl-Carrillo, Michelle; Gaedigk, Andrea (2021)
Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies

Tamm, R.; Maegi, R.; Tremmel, R.; Winter, S.; Mihailov, E.; Smid, A.; Moericke, A.; Klein, K.; Schrappe, M.; Stanulla, M.; Houlston, R.; Weinshilboum, R.; Rascan, Irena Mlinaric; Metspalu, A.; Milani, L.; Schwab, M.; Schaeffeler, E. (2017)
The choice of ultra-low attachment plates impacts primary human and primary canine hepatocyte spheroid formation, phenotypes, and function

Xing, Chen; Kemas, Aurino; Mickols, Evgeniya; Klein, Kathrin; Artursson, Per; Lauschke, Volker M. (2024)
The CYP2B6*6 Allele Significantly Alters the N-Demethylation of Ketamine Enantiomers In Vitro

Li, Yibai; Coller, Janet K.; Hutchinson, Mark R.; Klein, Kathrin; Zanger, Ulrich M.; Stanley, Nathan J.; Abell, Andrew D.; Somogyi, Andrew A. (2013)
The effect of genetic variants in the transcription factor TSPYL family on the CYP3A4 mediated cyclosporine metabolism in kidney transplant patients

Zhai, Qinglian; Moes, Dirk Jan A. R.; van Gelder, Teun; van der Lee, Maaike; Sanders, Jan-Stephan; Bemelman, Frederike J.; de Fijter, Johan W.; Klein, Kathrin; Schwab, Matthias; Swen, Jesse J. (2024)
The Letrozole Phase 1 Metabolite Carbinol as a Novel Probe Drug for UGT2B7

Precht, Jana C.; Schroth, Werner; Klein, Kathrin; Brauch, Hiltrud; Krynetskiy, Evgeny; Schwab, Matthias; Muerdter, Thomas E. (2013)
The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPAR alpha-tr, autonomously regulates proliferative and pro-inflammatory genes

Thomas, Maria; Bayha, Christine; Klein, Kathrin; Mueller, Simon; Weiss, Thomas S.; Schwab, Matthias; Zanger, Ulrich M. (2015)
Tri-Allelic Haplotypes Determine and Differentiate Functionally Normal Allele CYP2D6*2 and Impaired Allele CYP2D6*41

Zanger, Ulrich M.; Momoi, Kyoko; Hofmann, Ute; Schwab, Matthias; Klein, Kathrin (2021)
Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors

Riedmaier, A. Emami; Burk, O.; van Eijck, B. A. C.; Schaeffeler, E.; Klein, K.; Fehr, S.; Biskup, S.; Mueller, S.; Winter, S.; Zanger, U. M.; Schwab, M.; Nies, A. T. (2016)

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