Langzeituntersuchungen von 52 behandelten Patienten mit Gastrointestinalen Stromatumoren (GIST)

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URI: http://hdl.handle.net/10900/110345
http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-1103458
http://dx.doi.org/10.15496/publikation-51721
Dokumentart: Dissertation
Date: 2020-12-07
Source: erschienen in Translational Gastroenterol Hepatology 2018; 3:108
Language: German
Faculty: 4 Medizinische Fakultät
Department: Medizin
Advisor: Ladurner, Ruth (PD Dr.)
Day of Oral Examination: 2020-11-26
DDC Classifikation: 610 - Medicine and health
Keywords: Imatinib mesilat , Stroma , Tumor
Other Keywords: GIST
Gastrointestinale Stromatumore
Imatinib
License: Publishing license including print on demand
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Inhaltszusammenfassung:

Tumor location of GIST was gastric in 32, small bowel in 14, rectum in 3 and extraintestinal in 3 patients. Median tumor size was 46 mm. Median mitotic index was 4 per 50 hpf. Resection was achieved R0 in 46 patients, R1 in 4 patients and R2 in 2 patients. Mean overall survival was 58.9 months (range, 46– 73 months). Mean recurrence free survival was 45.6 months (range, 36–57 months). Mean overall survival was 58.9 months (range, 46–73 months). Risk factors for recurrence were tumor location and high mitotic index Ki-67.

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