Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Rodriguez-Martin, Bernardo; Alvarez, Eva G.; Baez-Ortega, Adrian; Zamora, Jorge; Supek, Fran; Demeulemeester, Jonas; Santamarina, Martin; Ju, Young Seok; Temes, Javier; Garcia-Souto, Daniel; Detering, Harald; Li, Yilong; Rodriguez-Castro, Jorge; Dueso-Barroso, Ana; Bruzos, Alicia L.; Dentro, Stefan C.; Blanco, Miguel G.; Contino, Gianmarco; Ardeljan, Daniel; Tojo, Marta; Roberts, Nicola D.; Zumalave, Sonia; Edwards, Paul A. W.; Weischenfeldt, Joachim; Puiggros, Montserrat; Chong, Zechen; Chen, Ken; Lee, Eunjung Alice; Wala, Jeremiah A.; Raine, Keiran; Butler, Adam; Waszak, Sebastian M.; Navarro, Fabio C. P.; Schumacher, Steven E.; Monlong, Jean; Maura, Francesco; Bolli, Niccolo; Bourque, Guillaume; Gerstein, Mark; Park, Peter J.; Wedge, David C.; Beroukhim, Rameen; Torrents, David; Korbel, Jan O.; Martincorena, Inigo; Fitzgerald, Rebecca C.; Van Loo, Peter; Kazazian, Haig H.; Burns, Kathleen H.; Campbell, Peter J.; Tubio, Jose M. C.; Akdemir, Kadir C.; Boutros, Paul C.; Bowtell, David D. L.; Brors, Benedikt; Chan, Kin; Cortes-Ciriano, Isidro; Dunford, Andrew J.; Edwards, Paul A.; Estivill, Xavier; Etemadmoghadam, Dariush; Feuerbach, Lars; Fink, J. Lynn; Frenkel-Morgenstern, Milana; Garsed, Dale W.; Gordenin, Dmitry A.; Haan, David; Haber, James E.; Hess, Julian M.; Hutter, Barbara; Imielinski, Marcin; Jones, David T. W.; Kazanov, Marat D.; Klimczak, Leszek J.; Koh, Youngil; Kumar, Kiran; Lee, Jake June-Koo; Lynch, Andy G.; Macintyre, Geoff; Markowetz, Florian; Martinez-Fundichely, Alexander; Meyerson, Matthew; Miyano, Satoru; Nakagawa, Hidewaki; Ossowski, Stephan; Pearson, John, V; Rippe, Karsten; Roberts, Steven A.; Scully, Ralph; Shackleton, Mark; Sidiropoulos, Nikos; Sieverling, Lina; Stewart, Chip; Villasante, Izar; Waddell, Nicola; Yang, Lixing; Yao, Xiaotong; Yoon, Sung-Soo; Zhang, Cheng-Zhong

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Autor(en):

Rodriguez-Martin, Bernardo; Alvarez, Eva G.; Baez-Ortega, Adrian; Zamora, Jorge; Supek, Fran; Demeulemeester, Jonas; Santamarina, Martin; Ju, Young Seok; Temes, Javier; Garcia-Souto, Daniel; Detering, Harald; Li, Yilong; Rodriguez-Castro, Jorge; Dueso-Barroso, Ana; Bruzos, Alicia L.; Dentro, Stefan C.; Blanco, Miguel G.; Contino, Gianmarco; Ardeljan, Daniel; Tojo, Marta; Roberts, Nicola D.; Zumalave, Sonia; Edwards, Paul A. W.; Weischenfeldt, Joachim; Puiggros, Montserrat; Chong, Zechen; Chen, Ken; Lee, Eunjung Alice; Wala, Jeremiah A.; Raine, Keiran; Butler, Adam; Waszak, Sebastian M.; Navarro, Fabio C. P.; Schumacher, Steven E.; Monlong, Jean; Maura, Francesco; Bolli, Niccolo; Bourque, Guillaume; Gerstein, Mark; Park, Peter J.; Wedge, David C.; Beroukhim, Rameen; Torrents, David; Korbel, Jan O.; Martincorena, Inigo; Fitzgerald, Rebecca C.; Van Loo, Peter; Kazazian, Haig H.; Burns, Kathleen H.; Campbell, Peter J.; Tubio, Jose M. C.; Akdemir, Kadir C.; Boutros, Paul C.; Bowtell, David D. L.; Brors, Benedikt; Chan, Kin; Cortes-Ciriano, Isidro; Dunford, Andrew J.; Edwards, Paul A.; Estivill, Xavier; Etemadmoghadam, Dariush; Feuerbach, Lars; Fink, J. Lynn; Frenkel-Morgenstern, Milana; Garsed, Dale W.; Gordenin, Dmitry A.; Haan, David; Haber, James E.; Hess, Julian M.; Hutter, Barbara; Imielinski, Marcin; Jones, David T. W.; Kazanov, Marat D.; Klimczak, Leszek J.; Koh, Youngil; Kumar, Kiran; Lee, Jake June-Koo; Lynch, Andy G.; Macintyre, Geoff; Markowetz, Florian; Martinez-Fundichely, Alexander; Meyerson, Matthew; Miyano, Satoru; Nakagawa, Hidewaki; Ossowski, Stephan; Pearson, John, V; Rippe, Karsten; Roberts, Steven A.; Scully, Ralph; Shackleton, Mark; Sidiropoulos, Nikos; Sieverling, Lina; Stewart, Chip; Villasante, Izar; Waddell, Nicola; Yang, Lixing; Yao, Xiaotong; Yoon, Sung-Soo; Zhang, Cheng-Zhong

Tübinger Autor(en):

Ossowski, Stephan

Erschienen in:

Nature Genetics (2020), Bd. 52, H. 3, S. 306-319

Verlagsangabe:

Nature Publishing Group

Sprache:

Englisch

Referenz zum Volltext:

http://dx.doi.org/10.1038/s41588-019-0562-0

ISSN:

1546-1718