IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling

Maity, Palash C.; Bilal, Mayas; Koning, Marvyn T.; Young, Marc; van Bergen, Cornelis A. M.; Renna, Valerio; Nicolo, Antonella; Datta, Moumita; Gentner-Goebel, Eva; Barendse, Rob S.; Somers, Sebastiaan F.; de Groen, Ruben A. L.; Vermaat, Joost S. P.; Steinbrecher, Daniela; Schneider, Christof; Tausch, Eugen; Bittolo, Tamara; Bomben, Riccardo; Mazzarello, Andrea Nicola; del Poeta, Giovanni; Kroes, Wilma G. M.; van Wezel, J. Tom; Imkeller, Katharina; Busse, Christian E.; Degano, Massimo; Bakchoul, Tamam; Schulz, Axel Ronald; Mei, Henrik; Ghia, Paolo; Kotta, Konstantia; Stamatopoulos, Kostas; Wardemann, Hedda; Zucchetto, Antonella; Chiorazzi, Nicholas; Gattei, Valter; Stilgenbauer, Stephan; Veelken, Hendrik; Jumaa, Hassan

IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling

Autor(en):

Maity, Palash C.; Bilal, Mayas; Koning, Marvyn T.; Young, Marc; van Bergen, Cornelis A. M.; Renna, Valerio; Nicolo, Antonella; Datta, Moumita; Gentner-Goebel, Eva; Barendse, Rob S.; Somers, Sebastiaan F.; de Groen, Ruben A. L.; Vermaat, Joost S. P.; Steinbrecher, Daniela; Schneider, Christof; Tausch, Eugen; Bittolo, Tamara; Bomben, Riccardo; Mazzarello, Andrea Nicola; del Poeta, Giovanni; Kroes, Wilma G. M.; van Wezel, J. Tom; Imkeller, Katharina; Busse, Christian E.; Degano, Massimo; Bakchoul, Tamam; Schulz, Axel Ronald; Mei, Henrik; Ghia, Paolo; Kotta, Konstantia; Stamatopoulos, Kostas; Wardemann, Hedda; Zucchetto, Antonella; Chiorazzi, Nicholas; Gattei, Valter; Stilgenbauer, Stephan; Veelken, Hendrik; Jumaa, Hassan

Tübinger Autor(en):

Bakchoul, Tamam

Erschienen in:

Proceedings of The National Academy of Sciences of The United States of America (2020), Bd. 117, H. 8, S. 4320-4327

Verlagsangabe:

Natl Acad Sciences

Sprache:

Englisch

Referenz zum Volltext:

http://dx.doi.org/10.1073/pnas.1913810117

ISSN:

0027-8424