Inhibition of DOT1L and PRMT5 promote synergistic anti-tumor activity in a human MLL leukemia model induced by CRISPR/Cas9

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Inhibition of DOT1L and PRMT5 promote synergistic anti-tumor activity in a human MLL leukemia model induced by CRISPR/Cas9

Author: Secker, Kathy-Ann; Keppeler, Hildegard; Duerr-Stoerzer, Silke; Schmid, Hannes; Schneidawind, Dominik; Hentrich, Thomas; Schulze-Hentrich, Julia M.; Mankel, Barbara; Fend, Falko; Schneidawind, Corina
Tübinger Autor(en):
Secker, Kathy-Ann
Keppeler, Hildegard
Schmid, Hannes
Schneidawind, Dominik
Hentrich, Thomas
Mankel, Barbara
Fend, Falko
Schneidawind, Corina
Dürr-Störzer, Silke
Schulze-Hentrich, Julia
Published in: Oncogene (2019), Bd. 38, H. 46, S. 7181-7195
Verlagsangabe: Nature Publishing Group
Language: English
Full text: http://dx.doi.org/10.1038/s41388-019-0937-9
ISSN: 1476-5594
DDC Classifikation: 570 - Life sciences; biology
610 - Medicine and health
Dokumentart: Artikel
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