Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole

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Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole

Author: Tuerk, Denise; Hanke, Nina; Wolf, Sarah; Frechen, Sebastian; Eissing, Thomas; Wendl, Thomas; Schwab, Matthias; Lehr, Thorsten
Tübinger Autor(en):
Schwab, Matthias
Published in: Clinical Pharmacokinetics (2019), Bd. 58, H. 12, S. 1595-1607
Verlagsangabe: Adis Int Ltd
Language: English
Full text: http://dx.doi.org/10.1007/s40262-019-00777-x
ISSN: 1179-1926
DDC Classifikation: 610 - Medicine and health
Dokumentart: Artikel
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