In Vitro Effects of the Second-Generation Proteasome Inhibitor Carfilzomib on Human Monocyte-Derived Dendritic Cells

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URI: http://hdl.handle.net/10900/100776
http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-1007764
http://dx.doi.org/10.15496/publikation-42156
Dokumentart: Dissertation
Date: 2020-05-19
Language: English
Faculty: 4 Medizinische Fakultät
Department: Medizin
Advisor: Grünebach, Frank (PD Dr. rer. nat.)
Day of Oral Examination: 2020-01-16
DDC Classifikation: 610 - Medicine and health
Keywords: Dendritische Zelle , Immunologie , Onkologie
Other Keywords: Carfilzomib
Immunology
Monocyte-Derived Dendritic Cells
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Abstract:

The objective of this project was on discovering a possible change in the MoDC phenotype and function due to carfilzomib exposure. MoDC function was tested with regard to cell viability, cytokine secretion and migration.

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