Auflistung nach Autor "Zimmermann, Markus O."

Development of tools and methods for the analysis, visualization, and prediction of halogen bonding in molecular design and drug design

Zimmermann, Markus O. (2015)

Dibenzosuberones as p38 Mitogen-Activated Protein Kinase Inhibitors with Low ATP Competitiveness and Outstanding Whole Blood Activity

Fischer, Stefan; Wentsch-Teltschik, Heike Kristin; Zimmermann, Markus O.; Bauer, Silke Mona; Storch, Kirsten; Nieß, Raimund; Koeberle, Solveigh Cornelia; Böckler, Frank; Laufer, Stefan (2013)

Discovery of Ircinianin Lactones B and C-Two New Cyclic Sesterterpenes from the Marine Sponge Ircinia wistarii

Majer, Thomas; Bhattarai, Keshab; Straetener, Jan; Pohlmann, Justus; Zimmermann, Markus O.; Schindler, Michael; Brötz, Heike; Böckler, Frank; Gross, Harald (2022)

Evaluating the Potential of Halogen Bonding in Molecular Design: Automated Scaffold Decoration Using the New Scoring Function XBScore

Zimmermann, Markus O.; Lange, Andreas; Böckler, Frank (2015)

Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen Bioisostere

Zimmermann, Markus O.; Böckler, Frank (2015)

Halogen-enriched fragment libraries as chemical probes for harnessing halogen bonding in fragment-based lead discovery

Zimmermann, Markus O.; Lange, Andreas; Wilcken, Rainer; Cieslik, Markus B.; Exner, Thomas Eckart; Koch, Pierre; Böckler, Frank (2014)

Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53

Wilcken, Rainer; Zimmermann, Markus O.; Böckler, Frank (2012)

Intramolecular signaling in tandem-GAF domains from PDE5 and PDE10 studied with a cyanobacterial adenylyl cyclase reporter

Banjac, Ana; Zimmermann, Markus O.; Kurz, Ursula; Schultz, Anita; Schultz, Joachim E.; Böckler, Frank (2012)

Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology

Wilcken, Rainer; Zimmermann, Markus O.; Lange, Andreas; Böckler, Frank (2013)

Quadruple Target Evaluation of Diversity-Optimized Halogen-Enriched Fragments (HEFLibs) Reveals Substantial Ligand Efficiency for AP2-Associated Protein Kinase 1 (AAK1)

Dammann, Marcel; Kramer, Markus; Zimmermann, Markus O.; Böckler, Frank (2022)

Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C

Stahlecker, Jason; Klett, Theresa; Schwer, Martin; Jaag, Simon; Dammann, Marcel; Ernst, Larissa N.; Braun, Michael B.; Zimmermann, Markus O.; Kramer, Markus; Lammerhofer, Michael; Stehle, Thilo; Böckler, Frank (2022)

Scaffold Effects on Halogen Bonding Strength

Lange, Andreas; Heidrich, Johannes; Zimmermann, Markus O.; Exner, Thomas Eckart; Böckler, Frank (2019)

Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes

Dammann, Marcel; Stahlecker, Jason; Zimmermann, Markus O.; Klett, Theresa; Rotzinger, Kilian; Kramer, Markus; Coles, Murray; Stehle, Thilo; Böckler, Frank (2022)

Synthesis of Amino Acids Bearing Halodifluoromethyl Moieties and Their Application to p53-Derived Peptides Binding to Mdm2/Mdm4

Vaas, Sebastian; Zimmermann, Markus O.; Klett, Theresa; Böckler, Frank (2023)

Targeting Histidine Side Chains in Molecular Design through Nitrogen-Halogen Bonds

Lange, Andreas; Wilcken, Rainer; Zimmermann, Markus O.; Böckler, Frank (2013)

Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond

Lange, Andreas; Zimmermann, Markus O.; Heidrich, Johannes; Hennig, Susanne; Schall, Christoph; Sievers-Engler, Adrian; Ansideri, Francesco; Koch, Pierre; Stehle, Thilo; Laufer, Stefan; Günther, Marcel Benjamin; Büttner, Felix Michael; Lämmerhofer, Michael; Böckler, Frank (2015)

Targeting the protein backbone with aryl halides: systematic comparison of halogen bonding and pi...pi interactions using N-methylacetamide

Zimmermann, Markus O.; Böckler, Frank (2016)

Tri- and Tetrasubstituted Pyrazole Derivates: Regioisomerism Switches Activity from p38MAP Kinase to Important Cancer Kinases

Arnsmann, Martina; Zimmermann, Markus O.; Koch, Pierre; Laufer, Stefan; Böckler, Frank (2012)

Using halogen bonds to address the protein backbone: a systematic evaluation

Wilcken, Rainer; Zimmermann, Markus O.; Lange, Andreas; Böckler, Frank (2012)

Using Surface Scans for the Evaluation of Halogen Bonds toward the Side Chains of Aspartate, Asparagine, Glutamate, and Glutamine

Zimmermann, Markus O.; Lange, Andreas; Böckler, Frank; Exner, Thomas Eckart (2016)

Auflistung nach Autor "Zimmermann, Markus O."

Auflistung nach Autor "Zimmermann, Markus O."

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