Auflistung nach Autor "Heintze, Tamara Sonja"

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CRISPR/Cas9-mediated genome editing of the cytochrome P450 system in the metabolically competent liver cell line HepaRG

Heintze, Tamara Sonja (2021)
CRISPR/Cas9-mediated genome editing of the cytochrome P450 system in the metabolically competent liver cell line HepaRG

Heintze, Tamara Sonja (2021-12-17)

HepaRG cells are a suitable in vitro human liver model for absorption, distribution, metabolism, and excretion (ADME) research and toxicity studies, as they express multiple cytochrome P450 (CYP) isozymes and exhibit several ...
Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells

Heintze, Tamara Sonja; Klein, Kathrin; Hofmann, Ute; Zanger, Ulrich M. (2021)
Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis

Heintze, Tamara Sonja; Schmidlin, Thierry; Hofmann, Ute; Zanger, Ulrich M.; Schwab, Matthias; Klein, Kathrin (2021)

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