This thesis is giving insight to the complex human-environmental linkages of global change. In order not to exceed the earth’s carrying capacity, a paradigm shift towards global sustainable development is inevitable. One ...
Nicht- oder falsch-reparierte Doppelstrangbrüche als Konsequenz einer Strahlen- bzw. Mutagenexposition können potentiell genotoxisch wirken und sich in Form von Chromosomenbrüchen und Chromosomentranslokationen im Genom ...
The present study investigates the role of Phosphoinositide 3 kinase (PI3K) pathway in the regulation of dendritic cell (DC) functions. DCs are antigen-presenting cells that provide a link between innate and adaptive ...
Environmental gradients constitute an extraordinary opportunity to study adaptation and evolution on a small spatial scale. Along such gradients abiotic and biotic factors fluctuate in space and time and allow studying the ...
ALK+ und ALK- anaplastische großzellige Lymphome (ALCL) weisen unterschiedliche miRNA-Signaturen auf, einschließlich einer niedrigen Expression von miR-146a, miR-181a und miR-26a bei ALK+ALCL. In dieser Studie wurden die ...
Everyday, in multicellular organisms several billions of cells die by programmed cell death type 1, apoptosis, whereby tissue homoeostasis is guaranteed. Dying and dead cells are engulfed by professional phagocytes without ...
Even the most complex organism has its origin in a single cell. During development the descendants of this cell adopt diverse fates in response to a variety of endogenous and exogenous factors, giving rise to the overwhelming ...