Peroxisomes, ubiquitous and highly dynamic organelles in eukaryotic cells, are crucial for human health and development. They are needed for oxidative metabolic processes, including the breakdown of fatty acids and the ...
The 55 kDa protein CD14 binds to lipopolysaccharide (LPS) and several other bacterial cell wall components. CD14 plays a central role in TLR2- and TLR4-mediated signaling in the innate immune response. To identify the ...
The ability of an organism to produce different phenotypes in response to environmental signals has been described as phenotypic plasticity. Plastic traits are ubiquitous in nature, and can have adaptive advantages as the ...
Retinitis pigmentosa (RP) groups a family of hereditary neurodegenerative diseases of the retina characterized by progressive loss of photoreceptors and for which treatment is still lacking. The aim of this thesis was to ...