2026-09-28T10:57:31Zhttps://publikationen.uni-tuebingen.de/oai/requestoai:publikationen.uni-tuebingen.de:10900/630002019-10-30T03:21:21Zcom_10900_42126col_10900_42130
Publikationssystem UB Tuebingen
advisor
Kremsner, Peter Gottfried (Prof. Dr.)
author
Löhr, Sascha Johannes Zo-Ri
2015-04-27T13:44:29Z
2015-05
429830777
http://hdl.handle.net/10900/63000
Proper malaria diagnosis depends on the detection of asexual forms of Plasmodium spp. in the blood. Thick blood smear microscopy is the accepted gold standard of malaria diagnosis and is widely implemented. Surprisingly, diagnostic performance of this method is not well investigated and many clinicians in African routine settings base treatment decisions independent of microscopy results. This leads to overtreatment and poor management of other febrile diseases. Implementation of quality control programmes is recommended, but requires sustained funding, external logistic support and constant training and supervision of the staff. This study describes an easily applicable method to assess the performance of thick blood smear microscopy by determining the limit of blank and limit of detection. These two values are representative of the diagnostic quality and allow the correct discrimination between positive and negative samples.
de
ubt-podok
Nachweisgrenzen der Mikroskopie von Plasmodium falciparum in einem endemischen Malariagebiet Zentralafrikas
PhDThesis
URL
https://publikationen.uni-tuebingen.de/xmlui/bitstream/10900/63000/1/Dissertation%20Sascha%20L%c3%b6hr%202015.pdf
File
MD5
fec242ae670157e18f518e498c77e9ae
1509679
application/pdf
Dissertation Sascha Löhr 2015.pdf
URL
https://publikationen.uni-tuebingen.de/xmlui/bitstream/10900/63000/3/Dissertation%20Sascha%20L%c3%b6hr%202015.pdf.txt
File
MD5
27b39b8083d28643b5494bf7deaac9b2
145491
text/plain
Dissertation Sascha Löhr 2015.pdf.txt